Manchester City are now the 7/5* favourites with Betfair to win the FA Cup after cruising through to the fifth round with a 5-0 demolition of Burnley at the Etihad Stadium.
Holders Chelsea are also safely through after goals from Willian and Callum Hudson-Odoi gave them a 2-0 win over Sheffield Wednesday at Stamford Bridge.
However, there were some high profile casualties elsewhere, with West Ham losing to AFC Wimbledon, who are currently bottom of League One. Everton fell to a last minute winner for Millwall at the Den and Tottenham were beaten at Crystal Palace.
United are at 11/2* across the board in the outright betting, with Chelsea at 5/1* with Betfred after the clubs were drawn to face each other in the fifth round.
Wolves are now the fourth favourites at odds of 10/1* generally, although they needed a 93rd minute equaliser from Matt Doherty to force a replay at Shrewsbury.
Watford are fifth in the market after knocking out Newcastle at St James’ Park despite making 11 changes from their last Premier League match. The Hornets are at 16/1* with Betfred.
|*All odds quoted are subject to change|